The Department of Neurological Surgery is dedicated to advancing the science of neurosurgery through innovative research that bridges laboratory discovery and patient care. Our investigators pursue groundbreaking studies aimed at improving outcomes for patients with complex neurological disorders while helping shape the future of neurosurgical treatment.
The Department of Neurological Surgery at the University of Chicago Medicine is proud to announce the establishment of the Section of Computational Neurosurgery, the first section of its kind in the nation. Designed to unite neurosurgery with artificial intelligence, machine learning, data science, and advanced computational methods, the new section will drive innovation across the continuum of neurosurgical care. The section is led by Antonio R. Porras, PhD, Scientific Director of the Section of Computational Neurosurgery, and Rohaid Ali, MD, Clinical Director of the Section of Computational Neurosurgery.
Spine Surgery research at the Department of Neurological Surgery research focuses on advancing the understanding and treatment of complex spinal disorders through clinical outcomes research, large-scale data analysis, and surgical innovation, led by Mohamad Bydon, MD. Spinal Fusion research is lead by Timothy Witham, MD. The Stereotactic and Functional Neurosurgery Section conducts innovative research aimed at advancing the understanding and treatment of neurological and neuropsychiatric disorders. Through clinical trials, outcomes research, advanced imaging, brain mapping, and neuromodulation studies, investigators explore the neural mechanisms underlying disease while developing novel therapeutic approaches to improve patient outcomes, led by Peter Warnke, MD, and David Satzer, MD. The Neurovascular Surgery Section, led by Issam Awad, MD, and Sean Polster, MD, and Ryan Naylor, MD, PhD, conducts innovative research aimed at advancing the understanding, diagnosis, and treatment of complex cerebrovascular diseases.
Drawing on a longstanding tradition of scientific discovery, investigators pursue basic science, translational, and clinical research to uncover the mechanisms underlying vascular disorders of the brain and spinal cord and develop new therapeutic strategies. Pediatric neurosurgery research within the Department of Neurological Surgery, led by Arthur J. DiPatri, Jr, MD, is dedicated to advancing the understanding and treatment of neurological disorders affecting children through innovative clinical, translational, and collaborative research. Closely aligned with the Margaret Hackett Family Program (MHFP), our faculty and researchers investigate a wide range of pediatric conditions involving the brain, spine, and nervous system, while contributing to multi-institutional research initiatives that expand knowledge of rare and complex disorders. NeuroOncology research within the Department of Neurological Surgery, led by Youssef Comair, MD, and Bakhtiar Yamini, MD, is dedicated to advancing the understanding and treatment of brain tumors through innovative basic, translational, and clinical research. Faculty investigators explore the molecular and cellular mechanisms that drive tumor growth, therapeutic resistance, and interactions with the immune system, while developing novel treatment strategies aimed at improving patient outcomes. The research conducted by the section of Neurosurgical Trauma and Critical Care, led by Paramita Das, MD studies the outcomes after traumatic brain injury and biomarkers of TBI.
The Surgery Brain Research Institute, an integral part of the medical center which houses the neurosurgical staff offices and Sean Mullan Library and Conference Room, also contains 6,000 square feet of space exclusively developed for neurosurgical research. The Department of Neurological Surgery has a research area that adjoins the clinical area and with the neurosurgical faculty offices, which occupies 24,000 square feet in the Surgery Brain Research Institute. The laboratories are well-equipped for channel studies, microfluorometry, blood flow measurement, cellular neurophysiology, molecular biology, pharmacology, microscopy, biochemistry, tissue culture, histology and animal pathology. Superb operating facilities are available in the building for animal experimentation. Hyde Park Labs, a state-of-the-art advanced sciences building, driven by The University of Chicago’s transformative science, engineering & quantum research, which available to residents as additional research space.
There are strong ancillary services in neurology, neuropathology, neurophysiology (including electroencephalography and video monitoring) and a sleep laboratory. Three full-time neuroradiologists, trained and experienced in interventional neuroradiology, work closely with the neurosurgical service. There are fourteen Advanced Practice Providers, trained in the management of neuroscience patients, who support both the pediatric and adult services.