International Stroke Conference 2023

The Neurovascular Surgery Research team led by Principal Investigator Issam Awad, the John Harper Seeley Professor of Neurological Surgery presented 13 original papers at the American Stroke Association International Stroke Conference in Dallas, Texas, February 7-10, 2023, more than any other team from a single institution. Most of the papers were presented by medical student, graduate student and postdoctoral trainees in the Awad lab.

Oral presentations included

“Prospective symptomatic hemorrhage rates and functional outcomes in trial eligible cavernous angiomas with symptomatic hemorrhage (CASH)"

“Changes in quantitative susceptibility mapping on MRI during prospective follow-up of CASH in trial readiness project”

and “In vivo permeability of the aging brain with cerebral microbleeds”

Moderated poster presentations included

“Transcriptomic signatures of individual cell types in cavernous angioma”

and “Multiplexed histopathological characterization of cerebral microbleeds in the aging brain”

Poster presentations included

“Plasma proteins in correlation with lesional iron content and permeability imaging in clinical trial of CASH”

“Association of quality of life domains and clinical symptoms in familial CCM”

"Effectiveness of minimally invasive surgery with thrombolysis for evacuation of ICH: Post hoc Bayesian analysis of a Phase 3 randomized controlled trial”

“Can the extended Glasgow outcome scale (e-gos) augment the interpretation of results of minimally invasive surgery for ICH and IVH that used mRS as primary outcome?”

“Association between neutrophil-lymphocyte ratio and 30-day infection and thrombolytic outcome after ICH: A Clear III analysis”

“Underlying intracranial atherosclerotic disease is associated with worse outcomes in acute large vessel occlusion undergoing endovascular thrombectomy”

“Impact of socioeconomic status on the access to specialized care and enrollment/adherence in clinical trial for CCM”, and “2022 Progress Updates on the cavernous angioma with symptomatic hemorrhage (CASH) research consortium projects"